Instrumentation must handle samples of a large variety of different formats such as blood collection devices, microtubes, microplates and capillaries. Sample and reagent identification has no margin for errors. Roche Diagnostics Ltd. employs state of the art technologies such as 2 dimensional barcodes and radio frequency transponders for identification purposes. The COBAS® AmpliPrep® specimen preparation process utilizes a patented closed sample input, output, process and transport device.